Kocitaf Tablet
₹ 2,199.00/-
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Composition
Dolutegravir (50mg)
Emtricitabine (200mg)
Tenofovir Alafenamide (25mg)
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Product Introduction
Kocitaf Tablet is a combination of antiretroviral medicines prescribed for treating HIV (human immunodeficiency virus) infection. It strengthens the immune system to combat HIV and manage or treat AIDS (acquired immunodeficiency syndrome).
This tablet restricts the growth of HIV in the body, reducing the risk of complications and improving lifespan. It is essential to take the medicine consistently, with or without food, at the same time each day to maximize effectiveness. Missing a dose can hinder recovery and treatment. Discontinuing treatment abruptly can reduce the potency of the medicine.
Common Side Effects:
- Insomnia
- Fatigue
- Headache
- Nausea
- Diarrhea
These side effects are generally mild and temporary. If they persist, consult a doctor. Stay hydrated to mitigate side effects. The medication may cause dizziness, so avoid driving or operating heavy machinery.
Usage Guidelines:
Always follow the prescribed dose and duration.
Take the tablet whole, with water. If swallowing is difficult, consult your doctor for alternatives.
Precautions:
- Consult your doctor if you are pregnant, breastfeeding, or have pre-existing health conditions.
- Regular blood tests may be required to monitor kidney and liver functions, blood counts, and other health metrics.
- Avoid breastfeeding if HIV-positive to prevent transmission.
- Practice safe sex methods to avoid HIV transmission during treatment.
- Therapeutic Effects of Kocitaf Tablet
- Controls HIV infection by reducing viral load.
- Maintains long-term viral suppression and delays disease progression.
- Single-tablet regimen simplifies treatment, improving adherence.
- Reduced risk of renal and bone toxicity.
Interactions
Inform your healthcare provider about all the medications, including:
- Prescription drugs
- Over-the-counter medications
- Nutritional supplements
- Herbal products
Interactions with other drugs can reduce the effectiveness of Kocitaf Tablet or cause adverse effects.
Additional Information
Storage: Store below 30°C, away from light and moisture.
Missed Dose: If a dose is missed, take the next dose at the scheduled time. Do not double the dose.
Keep Away: Store out of reach of children and pets.
Safety Advice
Pregnancy
Limited information is available. Consult your doctor if pregnant or planning pregnancy.
Breastfeeding
Not recommended as the medicine passes into breast milk and may harm the baby.
Liver
Exercise caution in patients with liver diseases. Inform your doctor of any liver conditions.
Lungs
Limited information on use in lung diseases. Inform your doctor before initiating therapy.
Alcohol
Consult your doctor regarding alcohol consumption during the treatment.
Driving
May cause dizziness. Avoid driving or operating heavy machinery.
Side Effects of Kocitaf Tablet
Serious Side Effects:
- Hepatitis B reactivation
- Increased risk of fractures
- Acute renal failure
Common Side Effects:
- Headache
- Nausea
- Diarrhea
- Fatigue
- Insomnia
Frequently Asked Questions (FAQs)
Q1. Can Kocitaf Tablet cure HIV?
No, Kocitaf Tablet is not a cure for HIV. It controls the virus, reduces its replication, and slows disease progression. Regular use as prescribed helps maintain viral suppression and protects the immune system.
Q2. Can Kocitaf Tablet affect cholesterol or blood sugar levels?
Yes, it may affect cholesterol and blood sugar levels. Regular monitoring is recommended, especially for those with pre-existing conditions like diabetes or high cholesterol. Lifestyle modifications or additional treatments may be required.
Q3. Is it safe to abruptly stop taking Kocitaf Tablet?
No, abrupt discontinuation may lead to viral rebound and decreased treatment effectiveness. Consult your doctor before making changes to your regimen.
Q4. Does Kocitaf Tablet affect the liver?
Patients with liver disease, including hepatitis B or C, have a higher risk of complications. Your doctor will carefully plan your treatment if you have liver conditions.
Q5. Can Kocitaf Tablet be used for children and adolescents?
Yes, it is approved for children and adolescents above a certain age and weight. Consult a pediatric HIV specialist for proper dosage and safety considerations.
Fact Box
- Molecule Name: Dolutegravir, Emtricitabine, Tenofovir Alafenamide
- Therapeutic Class: Antiretroviral
- Pharmacological Classes:
- Dolutegravir: Integrase strand transfer inhibitors
- Emtricitabine: Nucleoside reverse transcriptase inhibitor (NRTI)
- Tenofovir Alafenamide: Nucleotide reverse transcriptase inhibitor (NtRTI)
- Indications: HIV infection
References
- Descovy 200 mg/25 mg film-coated tablets – Summary of Product Characteristics (SmPC) – (emc). Published April 2022. Accessed May 22, 2023. Source
- Emtricitabine / Tenofovir Alafenamide – Patient | NIH. Published February 27, 2023. Accessed May 22, 2023. Source
- KD Tripathi, Antiviral Drugs (Anti-retrovirus), Essentials of Medical Pharmacology, 8th Edition, 2019, 860-872.
- Gilead Sciences, Inc., US Food & Drug Administration, Revised Sep 2017. Accessed August 22, 2023. Source
