Tenof 300mg Tablet
₹ 799.00/-
Tenof 300mg Tablet consists of Tenofovir Disoproxil Fumarate as the active ingredient, which belongs to the class of antiretroviral or antiviral medicines. It is primarily used to treat HIV (human immunodeficiency virus) and HBV (hepatitis B virus) infections. Tenofovir is a nucleotide reverse transcriptase inhibitor (NRTI) that works by blocking the enzymes essential for viral replication, such as HIV reverse transcriptase and hepatitis B DNA polymerase.
This medicine should always be taken in combination with other medicines to treat HIV infection. It is suitable for adults and adolescents aged 12 to 18 years. For HIV treatment, this medicine is prescribed to adolescents whose previous HIV medications are no longer effective due to resistance or side effects. The safety and efficacy of this tablet have not been studied in patients over 65 years of age.
Precautions:
Do not take Tenof 300mg Tablet if you have had a hypersensitivity reaction to Tenofovir disoproxil fumarate or any of its ingredients.
During treatment, your doctor may monitor blood counts, bone mineral density, liver, and kidney functions to avoid serious complications.
Patients with a history of heart failure, pancreatitis, bone disease (e.g., osteonecrosis), fractures, chronic hepatitis B or C, or kidney problems should inform their doctor before taking the medicine.
Tenof 300mg is not recommended for adolescents with existing kidney problems.
If you have lactose intolerance, inform your doctor prior to treatment.
Discuss with your doctor if you are planning to get pregnant, are pregnant, or may be pregnant. Breastfeeding is not recommended due to the potential transmission of HIV.
Indications:
Treatment of HIV and HBV infections
How it Works: Tenof 300mg Tablet inhibits the reverse transcriptase enzyme, which is responsible for converting HIV’s RNA into DNA. By blocking this enzyme, Tenofovir disrupts viral replication, leading to a decrease in viral load in the blood. This also increases the number of CD4 (T) cells, which helps the immune system fight infections. This reduces the risk of severe health complications related to a weakened immune system.
Drug Interactions: It is important to inform your doctor about any prescribed medications, over-the-counter drugs, nutritional supplements, or herbal products you are taking. Some medicines may interact with Tenofovir and cause undesirable side effects.
Storage Instructions:
- Store at a temperature not exceeding 30°C.
- Keep the medicine away from moisture, heat, and light.
- Do not freeze.
- Keep out of the reach of children and pets.
Dosage & Administration: The usual recommended dosage for Tenof 300mg Tablet is one tablet per day, with or without food. For both adults and children weighing over 3.5kg, the dose is generally 300mg per day. However, the specific dosage and administration frequency should be determined by your doctor based on your medical condition.
Safety Information:
Pregnancy:
Consult your healthcare provider if you are pregnant, planning to get pregnant, or think you may be pregnant. Your doctor will monitor the development of your pregnancy regularly during treatment.
Breastfeeding:
HIV-positive mothers are advised not to breastfeed due to the risk of transmitting HIV to the baby. For HBV-infected patients, breastfeeding may be permitted, but you should discuss it with your doctor first.
Lung Issues:
It is unclear if Tenof 300mg Tablet is safe for individuals with lung disease. Inform your doctor if you have a lung condition before starting the treatment.
Liver Issues:
Patients with liver conditions should use Tenof 300mg with caution. Always consult your physician before starting the medicine.
Alcohol:
Avoid consuming alcohol while taking Tenof 300mg Tablet, as this can increase the risk of liver damage.
Driving:
Tenof 300mg Tablet may cause vision problems and fatigue, making it unsafe to drive or operate machinery. Avoid such activities during treatment.
Side Effects:
Side effects are unwanted symptoms that may be caused by the medication. While not everyone experiences side effects, they can occur.
Serious Side Effects:
- Pancreatitis (pancreas issues)
- Kidney damage
- Rapid or deep breathing
- Drowsiness
- Nausea and vomiting
- Infections
- Lactic acidosis (a buildup of lactic acid in the blood)
- Common Side Effects:
- Headache
- Stomach pain
- Tiredness
- Bloating, flatulence
- Low phosphate levels in blood
- Diarrhea
- Dizziness
- Rash
- Weakness
Important Advice:
Always inform your doctor about any underlying infections. If you have advanced HIV (AIDS), treatment may lead to the worsening of infection or inflammation.
It is critical to inform your doctor if you are on other medications that may harm your kidneys.
Tenof 300mg Tablet does not reduce the risk of transmitting HBV to others through sexual contact or blood. Use precautions as directed by your doctor.
Frequently Asked Questions (FAQs):
Can I drink alcohol while on Tenof 300mg?
Alcohol consumption can increase the risk of liver damage while taking this medicine. It is advisable to avoid alcohol.
What laboratory tests are required before taking Tenof 300mg? Before starting the treatment, your healthcare provider may perform tests such as pregnancy, HBV infection, estimated creatinine clearance, serum creatinine, urine glucose, and urine protein.
How do I know if I am hypersensitive to Tenof 300mg?
Symptoms of hypersensitivity may include severe rash, muscle pain, fatigue, fever, facial swelling, difficulty breathing, and skin peeling. If you experience any of these, contact your healthcare provider immediately.
What are the symptoms of lactic acidosis?
Symptoms of lactic acidosis include unusual weakness, tiredness, muscle pain, breathing trouble, stomach pain, nausea, dizziness, lightheadedness, and irregular heartbeat.
Can I dissolve Tenof 300mg and drink it?
No, Tenof 300mg should not be dissolved. It should be swallowed whole with water according to the instructions from your doctor.
Fact Box:
- Molecule Name: Tenofovir Disoproxil Fumarate
- Therapeutic Class: Antiretrovirals
- Pharmacological Class: Nucleoside Reverse Transcriptase Inhibitors (NRTIs)
- Indications:
- HIV Infection
- Hepatitis B Infection
References:
- KD Tripathi, Antiviral Drugs (Anti-retrovirus), Essentials of Medical Pharmacology, 8th Edition, 2019, 860-872.
- Gilead Sciences, Inc., U.S. Food and Drug Administration, [Revised on Apr 2019], [Accessed on 19th May 2022], FDA Link.
- Cipla (EU) Limited, Electronic Medicines Compendium (emc), [Revised on Nov 2021], [Accessed on 19th May 2023], Emc Link.