Telura Tablet
₹ 1,350.00/-
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Product Overview:
Salt Composition:
- Lamivudine (300mg)
- Tenofovir disoproxil fumarate (300mg)
- Efavirenz (600mg)
- Emtricitabine (200mg)
Telura Tablet is a combination of three antiretroviral medicines: Lamivudine, Tenofovir disoproxil fumarate, and Efavirenz. It is prescribed for the treatment of HIV (human immunodeficiency virus) infection. This combination therapy helps boost the immune system to fight against HIV and manage or treat AIDS (acquired immunodeficiency syndrome). It works by inhibiting the growth of HIV in the body and reducing the risk of HIV-related complications, thereby improving an individual's lifespan.
How to Take Telura Tablet: For best results, it should be taken on an empty stomach, preferably at bedtime. Consistency in taking the medicine at the same time each day is vital for its effectiveness. Missing doses can reduce its efficacy, so it is crucial to complete the full prescribed course unless advised otherwise by your healthcare provider.
Common Side Effects:
- Impaired concentration
- Abnormal dreams
- Headache
- Nausea
- Weakness and fatigue
- Nasal congestion
- Diarrhea
- Rash
- Dizziness
- Trouble sleeping
- Pain
- Depression
- Cough
Most of these side effects are usually not serious and resolve within 2-4 weeks of treatment. However, if they persist or worsen, consult your doctor. As the medication may cause dizziness or drowsiness, it’s recommended to avoid activities that require full concentration, such as driving, while using this medication. Additionally, avoid alcohol consumption as it could intensify the side effects.
Precautions: Before starting the treatment, inform your doctor if you are pregnant, breastfeeding, or have any kidney, liver, or other medical conditions. Your doctor might suggest laboratory tests before and during the course of treatment to monitor blood counts, liver and kidney function, and overall health conditions.
HIV-positive individuals should not breastfeed or share personal items such as razors and toothbrushes. Always consult your doctor about safe sexual practices to prevent HIV transmission during intercourse.
Uses:
Treatment of HIV infection
Telura Tablet is not a cure for HIV or AIDS but helps manage the infection and improves quality of life. It prevents the HIV virus from multiplying in the body, enhances immune system functioning, and reduces the risk of complications like new infections.
Important Information:
Telura Tablet does not prevent HIV transmission to others.
It should not be used to prevent HIV after accidental exposure.
Take the medication as prescribed by your doctor, and do not skip doses to ensure its effectiveness and reduce the risk of the virus becoming resistant to treatment.
How Telura Tablet Works: The combination of Lamivudine, Tenofovir disoproxil fumarate, and Efavirenz works by:
Preventing HIV from multiplying in the body
Reducing the amount of HIV in the bloodstream
Increasing CD4 cells (white blood cells that help fight infections), which is essential for improving immunity in HIV-positive individuals.
Side Effects:
While most side effects are mild and go away on their own, some may require medical attention. Serious side effects may include:
- Rapid breathing
- Drowsiness
- Nausea, vomiting, and stomach pain
- Severe allergic reactions
- Severe mood disturbances, depression, and suicidal thoughts
- Confusion, forgetfulness, seizures, and tremors
- Liver toxicity
- Kidney damage
- Autoimmune disorders
Precautions & Safety Advice:
- Pregnancy: Telura Tablet may pose risks to the developing baby. It is generally unsafe during pregnancy unless the benefits outweigh the potential risks in life-threatening situations. Consult your doctor.
- Breastfeeding: It is likely safe to use during breastfeeding, as limited human data suggests it does not significantly affect the baby.
- Lung Issues: If you have lung problems, inform your doctor before starting treatment.
- Liver & Kidney Issues: Telura is probably safe for patients with liver disease, but consult your doctor to discuss any necessary dose adjustments.
- Alcohol: Avoid alcohol consumption with Telura Tablet as it may worsen side effects.
- Driving: Telura can make you feel drowsy or dizzy. Avoid driving until you understand how the medication affects you.
Missed Dose:
If you miss a dose, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to compensate for the missed one.
Quick Tips:
- Take Telura Tablet on an empty stomach, preferably at bedtime.
- Skipping doses can lead to treatment failure, so be consistent with your medication schedule.
- Avoid activities requiring full concentration, such as driving, if you experience dizziness or drowsiness.
- If you're pregnant, consult your doctor about effective contraception while taking Telura, as it can cause birth defects.
- Exercise regularly and take calcium and vitamin D as advised by your doctor to prevent bone weakening.
- Regular kidney and liver function monitoring may be required. Contact your doctor if you experience symptoms such as abdominal pain, loss of appetite, or jaundice.
Storage Instructions:
Store Telura Tablets below 30°C in their original container, out of reach of children.
Frequently Asked Questions (FAQs):
Q1: What should you not take with Telura Tablet?
It is not recommended to take Telura with other HIV medications unless directed by your healthcare provider. Inform your doctor about any other medications you are currently taking.
Q2: How should I store Telura Tablet?
Store below 30°C in its original container, and keep it away from children.
Q3: What should I do if I miss a dose of Telura Tablet?
Take the missed dose as soon as you remember. If it's almost time for the next dose, skip the missed one and continue your regular schedule. Do not take two doses to make up for the missed one.
Q4: What laboratory tests are needed before starting Telura treatment?
Tests include HBV infection screening, serum creatinine levels, estimated creatinine clearance, urine glucose, and protein tests.
Q5: How do I know if I am hypersensitive to Telura Tablet?
Look for symptoms like severe rash, swelling of the face or lips, or signs of Steven’s Johnson syndrome. Contact your doctor if any of these symptoms occur.
Fact Box:
- Molecule Name: Efavirenz, Lamivudine, Tenofovir disoproxil fumarate
- Therapeutic Class: Antiretroviral
- Pharmacological Class:
- Nucleoside reverse transcriptase inhibitors (NRTIs)
- Non-nucleoside reverse transcriptase inhibitors (NNRTIs)
- Indication: Human Immunodeficiency Virus (HIV-1) infection
References:
- Macleods Pharmaceuticals Limited, US Food and Drug Administration, [Revised on Mar 2019] [Accessed on 23rd Apr 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/210649s000lbl.pdf
- Clinical info HIV.gov, Efavirenz / Lamivudine / Tenofovir Disoproxil Fumarate – Patient | NIH (hiv.gov)
- KD Tripathi, Antiviral Drugs (Anti-retrovirus), Essentials of Medical Pharmacology, 8th Edition, 2019, 860-872.
