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Xapavir 50mg Tablet

₹ 1,099.00/-

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Product Description:

Active Ingredient:
  • Dolutegravir (50mg)
Xapavir 50mg Tablet is an antiviral drug categorized as an Integrase Strand Transfer Inhibitor (INSTI), with Dolutegravir as its active ingredient. It is used in the treatment of human immunodeficiency virus (HIV) infection. HIV is primarily transmitted through sexual contact or infected blood, often due to sharing needles or other drug paraphernalia.

It is recommended that Xapavir be taken alongside other HIV medications to effectively manage the condition.

Precaution:
Caution is advised for patients with liver impairment. The dosage may need to be adjusted, or extra monitoring may be required to ensure the drug's safety and efficacy.
During the early stages of HIV treatment, some patients may develop immune reconstitution syndrome, an inflammatory response to opportunistic infections. If you experience any concerns or notice any worsening symptoms, consult with your healthcare provider.
It is important to monitor for hypersensitivity reactions such as rash, blistering, or mucosal lesions. If a severe allergic reaction occurs, stop the medication immediately and seek medical attention.

Important Safety Information:
  • Pregnancy: Always consult your doctor before taking Xapavir if you are pregnant or planning a pregnancy.
  • Breastfeeding: Breastfeeding is not recommended as Dolutegravir may pass into breast milk and could harm your baby.
  • Liver Disease: Xapavir must be used with caution in patients with severe liver diseases. Your doctor may adjust the dosage accordingly.
  • Alcohol Consumption: It is highly recommended to avoid alcohol consumption during the course of treatment with Xapavir, as alcohol may affect the drug’s effectiveness.
  • Driving and Operating Machinery: This medication may cause dizziness and affect concentration, so avoid driving or operating heavy machinery.
Therapeutic Uses of Xapavir 50mg Tablet:
Xapavir 50mg Tablet is used to treat HIV (Human Immunodeficiency Virus). It works by inhibiting the action of integrase, an enzyme crucial for the virus’s replication. Additionally, it helps increase the CD4 cells, which play a significant role in the immune system, improving the body’s ability to fight infections.

How to Take Xapavir 50mg Tablet:
  • Dosage: Xapavir is taken orally. Your healthcare provider will determine the correct dose based on your specific condition.
  • Instructions: Swallow the tablet whole with water, with or without food. Do not chew or crush the tablet.
  • Missed Dose: If you miss a dose, take it as soon as possible. However, if it's almost time for your next dose, skip the missed dose. Do not double the dose.
Side Effects:
Serious Side Effects:
  • Allergic reactions (e.g., swelling, fever)
  • Liver inflammation or liver failure
  • Joint pain
  • Infections and inflammation
Common Side Effects:
  • Depression
  • Abnormal dreams, insomnia
  • Skin rashes or itching
  • Nausea, vomiting
  • Stomach discomfort
  • Headache
  • Diarrhea
  • Fatigue
Note: While side effects are possible, they may not affect everyone. If you experience any serious or persistent symptoms, seek medical attention immediately.

Drug Interactions:
It is essential to inform your healthcare provider about any other medications, including prescription, over-the-counter, vitamins, or herbal products you are taking. Certain drugs may interact with Xapavir and reduce its effectiveness or cause side effects.

Quick Tips:
  • HIV Prevention: Prevent the spread of HIV by not sharing needles or personal items that may carry blood or body fluids.
  • Treatment Adherence: Adhere to your prescribed treatment regimen for maximum effectiveness. Missing doses can lead to the virus becoming resistant to medications.
Frequently Asked Questions (FAQs):

Q 1. What medicines should I avoid with Xapavir?
Inform your healthcare provider of all the medications you are taking to avoid any adverse interactions with Xapavir.

Q 2. Who should not take Xapavir?
People who are allergic to Dolutegravir or any of the ingredients in Xapavir should avoid taking this medication.

Q 3. Can people with liver issues take Xapavir?
Xapavir is metabolized by the liver. Patients with liver problems should consult with their healthcare provider before using this medication. In cases of severe liver issues, an alternative treatment may be recommended.

Q 4. How does Xapavir work for HIV?
Xapavir inhibits integrase, a critical enzyme for HIV replication, thereby reducing viral load in the body. It also boosts CD4 cell counts, helping the immune system fight infections.

Q 5. What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it's nearly time for the next dose, skip the missed dose and return to your normal dosing schedule.

Q 6. Is it safe to drink alcohol during treatment with Xapavir?
No, alcohol can interfere with the effectiveness of the medication. It is strongly recommended to avoid alcohol consumption while using Xapavir.

Q 7. What are the long-term side effects of using Xapavir?
Long-term side effects may include liver damage, bone loss, kidney problems, and immune reconstitution syndrome. Regular monitoring by your healthcare provider is essential.

Storage:
Store Xapavir 50mg Tablets at room temperature, between 15°C to 25°C. Keep the medication out of reach of children and pets.

Manufacturer:
  • ViiV Healthcare
  • Pharmacological Class: Integrase Strand Transfer Inhibitor
  • Indications: Treatment of HIV
References:
  • Tivicay 10mg Tablets – Patient Information Leaflet (PIL) – EMC
  • ViiV Healthcare, U.S. Food & Drug Administration – FDA Label
  • Bertram G Katzung, Basic and Clinical Pharmacology, Antiviral Agents, 14th Edition, 2017
  • KD Tripathi, Essentials of Medical Pharmacology, 8th Edition, 2019
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