Viropil Tablet
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Salt Composition: Dolutegravir (50mg) + Lamivudine (300mg) + Tenofovir disoproxil fumarate (300mg)
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Product Description
Viropil Tablet is a combination of three antiretroviral medications—Dolutegravir, Lamivudine, and Tenofovir disoproxil fumarate. It is prescribed for the treatment of HIV (Human Immunodeficiency Virus) infection. The tablet helps in boosting immunity to manage HIV and aids in preventing AIDS (Acquired Immunodeficiency Syndrome) related complications.
Viropil restricts the growth of HIV, reducing the risk of HIV-related complications and improving lifespan. The medicine can be taken with or without food, but taking it consistently at the same time each day increases its effectiveness. It is essential to complete the entire course of treatment unless advised otherwise by your doctor. Discontinuing the medicine suddenly can compromise its effectiveness.
Common side effects include headaches, nasal congestion, diarrhea, nausea, weakness, tiredness, cough, and rash. These are generally temporary. However, if they persist or become serious, it’s important to consult your doctor. Some users may experience fatigue or weakness, so it's recommended to avoid driving if you feel affected. Drinking plenty of fluids can help alleviate these side effects.
Before starting treatment, consult your doctor if you are pregnant, breastfeeding, or have any existing medical conditions. Regular blood tests may be required to monitor liver and kidney functions, and if you are HIV positive, avoid breastfeeding and sharing personal items like razors or toothbrushes. Consult your doctor for safe sexual practices to prevent the transmission of HIV.
Uses of Viropil Tablet
HIV Infection
Viropil Tablet prevents HIV from multiplying in the body. It helps control the infection and strengthens the immune system, lowering the chances of new infections and improving quality of life. This medicine is typically taken alongside other antiretroviral medications.
However, it is important to note that Viropil is not a cure for HIV or AIDS and should not be used as a post-exposure prophylaxis after accidental exposure to HIV. The treatment must be adhered to as prescribed by your doctor to maximize its effectiveness and reduce the chances of HIV resistance to antiretroviral medicines.
Side Effects of Viropil Tablet
Most side effects of Viropil do not require medical intervention and resolve as the body adjusts to the medication. However, if the symptoms persist or worsen, it’s advisable to consult a healthcare provider.
Common Side Effects:
- Headache
- Fever
- Abdominal pain
- Weakness
- Diarrhea
- Nausea
- Vomiting
- Joint pain
- Insomnia (difficulty sleeping)
- Gastrointestinal disturbances
- Dizziness
- Abnormal dreams
- Depression
- Anxiety
- Itching
- Rash
- Fatigue
- Decreased phosphate levels in blood
- General discomfort
- Cough
- Increased transaminase levels in blood
- Hair loss
- Muscle disorders
Serious Side Effects:
- Rapid breathing
- Drowsiness
- Severe nausea, vomiting, and stomach pain
- Severe allergic reactions
- Severe mood changes (including depression and suicidal thoughts)
- Confusion, forgetfulness, seizures, and tremors
- Liver toxicity (yellowing of the skin or eyes, dark urine)
- Kidney damage
How to Use Viropil Tablet
Take Viropil Tablet exactly as prescribed by your doctor. Swallow it whole, and do not chew, crush, or break the tablet. It can be taken with or without food, but it is recommended to take it at the same time every day for consistency.
How Viropil Tablet Works
Viropil is an anti-HIV medication. It works by inhibiting the action of reverse transcriptase, an enzyme crucial for HIV replication. By blocking this enzyme, Viropil prevents the production of HIV and its spread in the body.
Safety Advice
- Pregnancy: Viropil is unsafe during pregnancy as there is evidence of risk to the developing baby. It may be prescribed in rare life-threatening cases if the benefits outweigh the risks. Always consult your doctor.
- Breastfeeding: There is limited information on the use of Viropil during breastfeeding. Please consult your doctor before use.
- Lungs: If you have lung disease, consult your doctor before using Viropil. Contact your doctor if you experience any respiratory symptoms.
- Liver: Viropil should be used with caution in patients with severe liver disease. Your doctor may need to adjust the dosage.
- Alcohol: Alcohol consumption should be cautious with Viropil. Please consult your doctor.
- Driving: If you experience side effects that impair your ability to focus or react, avoid driving.
What If You Forget to Take Viropil Tablet?
If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and return to your regular schedule. Do not double the dose.
Quick Tips for Using Viropil Tablet
- Viropil Tablet is used to treat HIV infection.
- Skipping doses increases the risk of treatment failure. Ensure all doses are taken at the prescribed times.
- Take Viropil on an empty stomach, preferably at bedtime.
- Inform your doctor if you have a history of hepatitis B.
- Do not take this medicine if you are pregnant or breastfeeding.
- It may decrease calcium levels, so your doctor might monitor your calcium and Vitamin D levels.
- Your liver function may be monitored during treatment. Inform your doctor if you notice any symptoms like yellowing of eyes or skin, dark urine, or stomach pain.
- Side Effects of Viropil Tablet (30's)
Serious Side Effects:
- Rapid breathing
- Drowsiness
- Nausea, vomiting, and stomach pain
- Severe allergic reactions
- Severe mood disturbances, depression, and suicidal thoughts
- Confusion, forgetfulness, seizures, and tremors
- Liver toxicity (yellow skin, dark urine, light-colored skin)
- Kidney damage
Common Side Effects:
- Bloating, flatulence
- Headache
- Sleeplessness
- Skin reactions
- Wheezing, swelling, or lightheadedness
- Hair loss
- Diarrhea
- Bone disorders
- Weakness
- Anemia
Word of Advice
Always inform your doctor about any existing infections. In advanced HIV (AIDS) cases, signs of infection or inflammation might worsen once treatment starts.
If you are taking other medications that may affect your kidneys, inform your doctor.
Viropil does not reduce the risk of transmitting HIV to others via sexual contact or blood contamination. Continue your medication as prescribed and use effective contraception for safe sex practices.
Frequently Asked Questions (FAQs)
Q1. When should you report to your healthcare provider while taking Viropil?
Report to your healthcare provider if you experience symptoms of hypersensitivity reactions, lactic acidosis, or any other side effects. If you overdose on Viropil, seek medical help immediately.
Q2. Can I compensate for the missed dose of Viropil?
Do not compensate for a missed dose. Take it as soon as you remember or skip it if the next dose is near. Never double-dose.
Q3. Is it okay to refrigerate Viropil?
No, store Viropil tablets below 30°C in the original container, away from children.
Q4. What are the symptoms of lactic acidosis?
Symptoms include unusual weakness, tiredness, muscle pain, trouble breathing, stomach pain, nausea, vomiting, dizziness, lightheadedness, irregular heartbeat, and feeling cold in the limbs.
Q5. How can I manage side effects while taking Viropil?
Consult your doctor if you experience side effects. Your doctor may recommend over-the-counter or prescription medications to manage these symptoms.
Fact Box for Viropil Tablet (30's)
- Molecule Name: Dolutegravir + Lamivudine + Tenofovir disoproxil fumarate
- Therapeutic Class: Antiretrovirals
- Pharmacological Class:
- Integrase inhibitor
- Nucleoside reverse transcriptase inhibitors (NRTIs)
- Indications: HIV-1 Infection
References:
- Aurobindo Pharma, US Food and Drug Administration, Revised on Apr 2018.
- KD Tripathi, Essentials of Medical Pharmacology, 8th Edition, 2019.
