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Spegra Tablet

₹ 2,699.00/-

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Composition & Ingredients
Spegra Tablet is a combination of three antiretroviral medicines used to treat HIV infection:
  • Dolutegravir (50mg)
  • Emtricitabine (200mg)
  • Tenofovir Alafenamide (25mg)

Product Introduction
Spegra Tablet is prescribed for the treatment of HIV (human immunodeficiency virus) infection. It helps boost immunity, slowing down the progression of HIV and managing AIDS (acquired immunodeficiency syndrome).

This medication restricts the growth of HIV, reducing complications and improving the lifespan of an individual. It should be taken regularly to maintain its effectiveness. Do not miss doses, as it may impact recovery. Complete the full course unless advised otherwise by your doctor. Abruptly stopping the medication can reduce its effectiveness.

Uses of Spegra Tablet

HIV Infection
  • Controls HIV growth in the body.
  • Strengthens the immune system.
  • Reduces the risk of further infections.
  • Improves overall quality of life.

Note: Spegra Tablet is not a cure for HIV/AIDS. It must be used with other antiretroviral drugs to prevent the virus from developing resistance.

Dosage & How to Use

Take Spegra Tablet as prescribed by your doctor.
Swallow the tablet whole—do not chew, crush, or break it.
Can be taken with or without food, preferably at a fixed time daily.
If you miss a dose, take it as soon as possible. If it is almost time for your next dose, skip the missed dose—do not double up.

How Spegra Tablet Works

Spegra Tablet contains three antiretroviral medicines that work together:
Dolutegravir: Prevents the action of integrase, an enzyme that HIV needs to replicate.
Emtricitabine: Blocks reverse transcriptase, preventing HIV from multiplying.
Tenofovir Alafenamide: Stops HIV from infecting healthy cells.

Side Effects of Spegra Tablet

Common Side Effects
  • Insomnia (difficulty sleeping)
  • Headache
  • Nausea
  • Fatigue
  • Diarrhea
  • Serious Side Effects
  • Hepatitis B reactivation
  • Increased risk of fractures
  • Acute renal failure

Tip: Drinking plenty of fluids can help reduce side effects. If side effects persist or worsen, consult your doctor.

Safety Advice & Precautions

Pregnancy & Breastfeeding
Pregnancy: Limited data on safety. Consult your doctor before use.
Breastfeeding: Not recommended, as Spegra Tablet may pass into breast milk and harm the baby.

Alcohol
Avoid alcohol, as it may reduce drug effectiveness and cause toxic side effects.

Driving & Machinery
Spegra Tablet may cause dizziness. Avoid driving or operating heavy machinery.

Liver & Kidney Health
Liver Diseases: Dose adjustments may be required. Inform your doctor before use.
Kidney Function: Regular monitoring recommended.

Lungs
Unknown safety for patients with lung diseases. Consult a doctor before use.

Quick Tips
✔ Take Spegra Tablet at the same time daily for maximum effectiveness.✔ Although it reduces transmission risk, it does not prevent HIV spread—use condoms.✔ If infections appear soon after starting treatment, inform your doctor—it may indicate an immune response.✔ Can weaken bones—consider calcium & vitamin D supplements.

Word of Advice
If you have HIV or are at risk, consult a healthcare provider for proper treatment and prevention. Adherence to antiretroviral therapy is crucial to prevent drug resistance and maintain viral suppression. Regular check-ups, safe sex practices, and other preventive measures can help manage HIV effectively.

FAQs

Q1: Can Spegra Tablet cure HIV?
No, it does not cure HIV. It controls the virus, reduces its replication, and slows down disease progression. Long-term treatment is necessary.

Q2: Does Spegra Tablet affect cholesterol or blood sugar levels?
Yes, it may impact cholesterol and blood sugar levels. Patients with diabetes or high cholesterol should have regular monitoring.

Q3: Is Spegra Tablet safe for children and adolescents?
Yes, but only above a certain age and body weight. Pediatric HIV specialists should determine appropriate dosages.

Q4: Can Spegra Tablet affect the liver?
Yes, patients with hepatitis B or C are at risk of severe liver complications. Consult your doctor for a suitable treatment plan.

Q5: Is it safe to stop taking Spegra Tablet suddenly?
No, abruptly stopping can cause viral rebound and reduce treatment effectiveness. Always consult your doctor before stopping.

Fact Box
  • Molecule Name: Dolutegravir, Emtricitabine, Tenofovir Alafenamide
  • Therapeutic Class: Antiretroviral
  • Dolutegravir: Integrase Strand Transfer Inhibitors
  • Emtricitabine: Nucleoside Reverse Transcriptase Inhibitor
  • Tenofovir Alafenamide: Nucleotide Reverse Transcriptase Inhibitor (NtRTI)
  • Indication: HIV Infection
References
  • Summary of Product Characteristics (SmPC) – medicines.org.uk
  • Emtricitabine/Tenofovir Alafenamide – NIH Clinical Info
  • Essentials of Medical Pharmacology, 8th Edition – KD Tripathi
  • Gilead Sciences, Inc. – FDA Drug Label
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